高斌 副教授 硕士生导师
E-mail：gaobin@bjut.edu.cn
教育背景
2004-2008，威尼斯wns.8885556生命科学与生物工程学院，学士
2008-2013，威尼斯wns.8885556生命科学与生物工程学院，博士
工作经历
2013-2017，威尼斯wns.8885556生命科学与生物工程学院，讲师
2017-至今，威尼斯wns.8885556威尼斯wns.8885556，副教授
研究方向
心脑血管血流动力学与生物力学
在基础研究方面，提出了人工心脏生理控制的方法，用于诱导心脏功能的恢复。即实现了对人工心脏工作状态、器官灌注要求的满足、血管纤维化的保护、心肌收缩力的恢复、生物标记物的检测等整体的系统控制。在应用基础研究方面，开发了人工心脏样机2款，动物实验都已经成功。通过动物实验研究了人工心脏的器官灌注效果、血流动力学特性、生理控制、手术规划、生物形容性、血液相容性、人工心脏与受体的相互作用等。各种指标在国内同行中是处在领先水平。
主要科研项目
1. 科技部重点研发计划项目“血液损伤机制和生机电系统动力学机制研究”
2. 科技部重点研发计划项目“超早产儿体外生命支持：人工子宫新设备和关键技术研究”
3. 国家自然科学基金重点项目“基于多模态影像信息的搏动性耳鸣机制研究”
4. 国家自然科学基金重大研究计划“流固耦合问题的并行数值模拟算法与应用”
5. 国家自然科学基金面上项目“基于多模态影像及多物理场耦合的静脉性耳鸣骨壁重建后复发机制研究”
6. 国家自然科学基金青年项目“心室辅助对主动脉血流旋动流特性影响的血流动力学研究”
主要论文论著
发表SCI检索论文：
1. Xue Q, Ren X, Gao B, Li S, Song Z, Ding J, Chang Y. Hemodynamic investigation of a novel rotary displacement blood pump for extracorporeal membrane oxygenation. Int J Numer Method Biomed Eng. 2023 Jun;39(6):e3705.
2. Ma X, Gao B, Tao L, Ding J, Li S, Qiao A, Chang Y. Hemodynamic study of the effect of the geometric height of leaflets on the performance of the aortic valve under aortic valve reconstruction. J Thorac Dis. 2022 May;14(5):1515-1525.
3. Mu Z, Li X, Zhao D, Qiu X, Dai C, Meng X, Huang S, Gao B, Lv H, Li S, Zhao P, Liu Y, Wang Z, Chang Y. Hemodynamics study on the relationship between the sigmoid sinus wall dehiscence and the blood flow pattern of the transverse sinus and sigmoid sinus junction. J Biomech. 2022 Apr;135:111022.
4. Liu L, Mu Z, Kang Y, Huang S, Qiu X, Xue X, Fu M, Xue Q, Lv H, Gao B, Li S, Zhao P, Ding H, Wang Z. Hemodynamic mechanism of pulsatile tinnitus caused by venous diverticulum treated with coil embolization. Comput Methods Programs Biomed. 2022 Mar;215:106617.
5. Mu Z, Liu L, Sun Y, Gao B, Lv H, Zhao P, Liu Y, Wang Z. Multiphysics coupling numerical simulation of flow-diverting stents in the treatment of patients with pulsatile tinnitus. Int J Numer Method Biomed Eng. 2021 Dec;37(12):e3526.
6. Fu M, Liu G, Wang W, Gao B, Ji B, Chang Y, Liu Y. Hemodynamic evaluation and in vitro hemolysis evaluation of a novel centrifugal pump for extracorporeal membrane oxygenation. Ann Transl Med. 2021 Apr;9(8):679.
7. Huang S, Li X, Xue X, Qiu X, Mu Z, Fu M, Gao B, Zhao P, Wang Z. Hemodynamic study of the therapeutic effects of the different degrees of sigmoid sinus diverticulum reconstruction on patients. Med Eng Phys. 2020 Dec;86:8-15.
8. Gao B, Kang Y, Zhang Q, Chang Y. Biomechanical effects of the novel series LVAD on the aortic valve. Comput Methods Programs Biomed. 2020 Dec;197:105763.
9. Gao B, Zhang Q. Biomechanical effects of the working modes of LVADs on the aortic valve: A primary numerical study. Comput Methods Programs Biomed. 2020 Sep;193:105512.
10. Mu Z, Qiu X, Zhao D, Li X, Fu M, Liu Y, Gao B, Zhao P, Wang Z. Hemodynamic study on the different therapeutic effects of SSWD resurfacing surgery on patients with pulsatile tinnitus. Comput Methods Programs Biomed. 2020 Jul;190:105373.
11. Gao B, Zhang Q, Chang Y. Hemodynamic effects of support modes of LVADs on the aortic valve. Med Biol Eng Comput. 2019 Dec;57(12):2657-2671.
12. Zhang Q, Gao B, Chang Y. The numerical study on the effects of cardiac function on the aortic oxygen distribution. Med Biol Eng Comput. 2018 Jul;56(7):1305-1313. doi: 10.1007/s11517-017-1777-9.
13. Zhang Y, Gao B, Yu C. The hemodynamic effects of the LVAD outflow cannula location on the thrombi distribution in the aorta: A primary numerical study. Comput Methods Programs Biomed. 2016 Sep;133:217-227.
14. Gao B, Chang Y, Xuan Y, Zeng Y, Liu Y. The hemodynamic effect of the support mode for the intra-aorta pump on the cardiovascular system. Artif Organs. 2013 Feb;37(2):157-65.
15. Gao B, Chang Y, Gu K, Zeng Y, Liu Y. Physiological controller of an intra-aorta pump based on baroreflex sensitivity. Artif Organs. 2012 Dec;36(12):1015-25.
16. Gao B, Chang Y, Gu K, Zeng Y, Liu Y. A pulsatile control algorithm of continuous-flow pump for heart recovery. ASAIO J. 2012 Jul-Aug;58(4):343-52.
17. Gao B, Chang Y, Gu K, Zeng Y, Liu Y. Baroreflex sensitivity controller by intra-aortic pump: a potential benefit for heart recovery. ASAIO J. 2012 May-Jun;58(3):197-203.
18. Gao B, Gu K, Zeng Y, Chang Y. An anti-suction control for an intra-aorta pump using blood assistant index: a numerical simulation. Artif Organs. 2012 Mar;36(3):275-82.
19. Gao B, Gu K, Zeng Y, Liu Y, Chang Y. A blood assist index control by intraaorta pump: a control strategy for ventricular recovery. ASAIO J. 2011 Sep-Oct;57(5):358-62.
20. Chang Y, Gao B, Gu K. A model-free adaptive control to a blood pump based on heart rate. ASAIO J. 2011 Jul-Aug;57(4):262-7.
21. Gao B, Nie LY, Chang Y, Zeng Y. Physiological control of intraaorta pump based on heart rate. ASAIO J. 2011 May-Jun;57(3):152-7.
22. Chang Y, Gao B. A global sliding mode controller design for an intra-aorta pump. ASAIO J. 2010 Nov-Dec;56(6):510-6.
出版专著：
1. 常宇，高斌，李澍主编，生命支持装置前沿理论与技术：血流动力学[M]. 北京：中国科学技术出版社，2023.
2. 常宇，高斌主编. 心力衰竭的集中参数模型研究[M]. 北京：科学出版社, 2014
3. 常宇，高斌主编. 心室卸载生理控制模式设计及其血流动力学特性研究[M]. 北京：科学出版社, 2014
